Editors: Dr. Mani Jayakumar

Dr. Natchimuthu Karmegam (2022)

ISBN: 978-93-94174-05-4

Formulation and Evaluation of Novel Herbal Gel of Mimusops elengi Linn., fruits extract

R. Bhramaramba^1*, V. Anitha Kumari², V. Mrudula Raj³

¹Department of Pharmacology, Sir C R Reddy College of Pharmaceutical Sciences, Eluru, Eluru dst., Andhra Pradesh, India ²Department of Pharmaceutical Analysis, Sir C R Reddy College of Pharmaceutical Sciences, Eluru, Eluru dst., Andhra Pradesh, India ³Department of Pharmacy Practice, Sir C R Reddy College of Pharmaceutical Sciences, Eluru, Eluru dst., Andhra Pradesh, India

Herbal medicine has become an item of global importance both medicinal and economical. Although usage of these herbal medicines has increased, their quality, safety and efficiency are serious concerns in industrialized and developing countries. The present research has been undertaken with the aim to formulate and evaluate the herbal gel containing Mimusops elengi Linn., fruits extract. The gel formulation was designed by using Carbapol 940, Mimusops elengi Linn., fruits extract, propylene glycol, methyl paraben, propyl paraben and required amount of distilled water. The skin pH (6.8-7.1) was maintained by drop wise addition of Tri-ethanolamine. The physicochemical Parameters of formulations (pH, Spreadibility, Stability etc.) were determined. Stability studies have carried out as per ICH guidelines for 3 months at different temperatures and humidity. The results showed that formulation containing Mimusops elengi Linn., fruits extract Show better stability. Further formulations have studied for skin irritation on animal model (Rat) and result showed that there was no skin irritation to animals.

*Corresponding author; e-mail: bhramasristi@gmail.com

Cite this Chapter: Bhramaramba, R., V. Anitha Kumari and Mrudula Raj, V., 2022. Formulation and Evaluation of Novel Herbal Gel of Mimusops elengi Linn., fruits extract. In: M. Jayakumar and N. Karmegam (Eds.), Recent Trends in Bioresource Management for Greener Environment. Excellent Publishers, India. pp. 220-227. doi: https://doi.org/10.20546/978-93-94174-05-4_13