Transdisciplinary Science: Mapping the Future of Research pp 59-79
Editors: Dr Mukul Kumar Baruah, Dr Rahul Kanti Nath & Dr Joyobrato Nath (2025)
ISBN: 97978-93-94174-62-7
doi : https://doi.org/10.20546/978-93-94174-62-7_6
Chapter 6
Lifestyle and Dietary Interventions in Neuro-degeneration and Neuroprotection
Trisha Chakraborty
Department of Biotechnology and Microbiology, School of Natural Sciences, Techno India University, Tripura, Agartala, Tripura - 799004, India
Sudeshna Acharya
Department of Biotechnology and Microbiology, School of Natural Sciences, Techno India University, Tripura, Agartala, Tripura - 799004, India
Rahul Kanti Nath
Department of Chemistry, Cachar College, Silchar, Cachar, Assam - 788001, India
Anupam Das Talukdar
Department of Life Science and Bioinformatics, Assam University, Silchar, Cachar Assam - 788011, India
Rajat Nath*
Department of Biotechnology and Microbiology, School of Natural Sciences, Techno India University, Tripura, Agartala, Tripura - 799004, India
Abstract
With the advancing world, people are making dynamic changes to their lifestyles and diet pattern. These dynamic changes often sideline the intake of nutrients necessary for our body increasing the exposure to neurological disorders like neurodegeneration. The risk of developing neurodegenerative diseases (NDs) is not limited to the elderly population, in recent times a considerable percentage of young people have a share in the global prevalence of NDs. Apart from genetic and environmental causes, the lifestyle and diet of an individual also majorly effects the brain metabolism. Studies have shown that making changes in our sleeping pattern, diet and physical activity drastically improves brain metabolism and leads to development of neuroprotective mechanism. Mediterranean diet is one such healthy and effective dietary pattern which has been proven to be effective in decreasing the risk of Alzheimer’s disease development. Other diet models such as MIND, DASH diets also incorporate neuroprotective nutrients. Aerobic exercise and resistance exercise is found to increase cognitive function and also induces the release of neurotrophins which regulates neurogenesis. The gut-brain axis also significantly influences brain health, an imbalance in the gut microbe composition can lead to detrimental results in the brain. Thus, adopting a brain healthy lifestyle through physical exercise, sleep management, gut health maintenance and a nutrient-rich diet can mitigate the risk of neurodegeneration.
Keywords
Neurodegeneration, Lifestyle, Diet, Gut-Brain Axis, neuroprotection
Cite this Chapter: Trisha Chakraborty, Sudeshna Acharya, Rahul Kanti Nath, Anupam Das Talukdar and Rajat Nath. 2025. Lifestyle and Dietary Interventions in Neurodegeneration and Neuroprotection. In: Mukul Kumar Baruah, Rahul Kanti Nath and Joyobrato Nath (Eds.), Transdisciplinary Science: Mapping the Future of Research. Excellent Publishers, India. pp. 59-79. doi: https://doi.org/10.20546/978-93-94174-62-7_6
